We have developed the world’s only real-time, point-of-care blood propofol monitor
20m ICU patients sedated globally, 19m colonoscopies each year in US alone. No bedside propofol monitor. Until now.
What is Propofol?
Propofol is an intravenous drug used worldwide to sedate patients in intensive care and during medical procedures.
In ICUs, it is often given continuously for days, with dose adjustments guided by sedation scores rather than direct measurement of the drug in the bloodstream.
Without knowing the blood concentration, small inaccuracies compound, leading to prolonged ventilation, delayed recovery, avoidable complications, and significant cost.
Propofol is also used for procedures such as colonoscopy. Here, the challenge is different: not just delivering the right dose, but knowing when blood levels have fallen enough for safe cognitive and motor recovery.
The recovery threshold is well defined in the literature. Yet today, clinicians have no bedside method to confirm it.
When a drug is used this widely, this frequently, and this continuously, measurement is not optional, it is essential.
The Global Blind Spot
The cost of not measuring, is more than financial.
A single missing measurement has real implications
Real Savings
At a price of approximately $40 (£31 equivalent), modelling indicates that each ProSed® test generates roughly $80 (£62) in downstream ICU savings, representing an estimated 2:1 return.
Direct Clinical Impact
Sedation depth and duration are directly linked to ventilation time, delirium risk, and long-term outcomes in critically ill patients.
Preventable Cost
The economic burden associated with sedation-related complications in critical care runs into billions annually, driven by prolonged ventilation, delirium, and extended ICU length of stay.
ProSed®: Point-of-Care Propofol Monitoring
Bedside Immunoassay
Single-use test cartridge
Just one drop of blood required
Fully quantitative result in minutes
Fits seamlessly into ICU and procedural workflows
Enables personalised, optimised sedation
In development | Target launch ~2030ProTIVA™ builds on the ProSed® platform by delivering real-time, continuous propofol measurement during total intravenous anaesthesia (TIVA).
Supported by patients and by ICU Leaders
"I think that ProSed® will be a very valuable device, with clear application in both anaesthesia and critical care"
Professor David Menon
Consultant, Neuro/Trauma Critical Care Unit, Addenbrooke’s Hospital, Cambridge, UK
“Point-of-care propofol levels will be a gamechanger in intensive care and theatres"
Dr Connor Brown
Anaesthetist and intensive care doctor, London, UK
“The delirium was terrible. I saw babies floating around me. There was a fire. I couldn’t help”
ICU Survivor
Patient member of ICUSteps
(ICU Charity)
Contact Us
Somnus Scientific Limited
Future Space UWE North Gate,
Filton Road,
Bristol
BS34 8RB
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