Real-Time Blood Propofol Concentration Monitoring
FEATURED
Benefits of using propofol with patients who have cancer.
Somnus Research
SOMNUS n. som-nuhs:
The Roman god of sleep. The personification of sleep. Greek counterpart is Hypnos.
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Things are changing fast at Somnus Scientific as we develop our products and engage with more people. We are also finding more interest from agencies and the media.
What can we learn from COVID
Artificial Intelligence in anaesthesia
Measuring blood propofol concentration after procedural sedation
Video Spotlight
Somnus explains the new products being developed by Somnus and how they can benefit patients and clinicians
Somnus Business development Lead Malcolm Stewart explains…
We are developing...
A Suite Of Products To Measure Blood Propofol Concentration At the Point of Care
There is mounting evidence that patients given sedation (for instance in intensive care) are frequently over-sedated. As a result, they take longer to get off breathing machines (ventilators), stay in ICU longer than they need to, and are less likely to survive. Propofol is the most commonly used sedative in the majority of ICUs but there is currently no way of measuring how much is in the patients’ blood stream in real-time.
Despite increasing evidence of benefits to patients and the environment of using Total Intravenous Anaesthesia (TIVA) rather than volatile or gaseous anaesthesia, adoption of TIVA by clinicians is limited partly by the lack of a real-time blood propofol concentration monitor.
Somnus Scientific Limited is developing a suite of products to fill these gaps
What is Propofol?
Propofol Is An Intravenous Hypnotic Drug
It is short acting and so needs to be given by continuous infusion into a vein for all but the quickest procedures. In low dose it produces sedation (makes the patient sleepy) and if higher doses are given it produces general anaesthesia (unconsciousness).
Many patients require sedation to tolerate treatments (such as being on a ventilator in ICU) or procedures (such as colonoscopy – a camera examination of the inside of the bowel). Published research shows that it is not always easy to get the dose right with some patients receiving too much and others too little
When it is administered by continuous infusion to maintain anaesthesia (keep people unconscious) it has substantial benefits for patients compared with the use of anaesthetic gases. These benefits include a carefully controlled, smooth induction of anaesthesia and a rapid, high quality recovery with a very low incidence of nausea. Propofol appears to have less impact on memory, especially in susceptible patients. Retrospective analysis suggests that patients who have cancer and are anaesthetised with propofol are more likely to be alive 5 years later than those given gaseous anaesthesia. Emerging laboratory evidence is helping to explain this.
Learn moreEvidence
TIVA has benefits for patients including fewer symptoms such as postoperative nausea and vomiting and a better recovery profile.
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Watch this space for news about the Somnus Scientific Advisory Board.
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Read MoreOur innovation supports the development of personalized sedation and anaesthesia; precision medicine for individual patients. By meeting the needs of clinicians we will make sedation and anaesthesia safer for patients and better for the environment.
Read MoreNew press release on the Somnus Scientific site.
Read MoreMediLink South West awards:“This year’s Partnership between Academia and Business Award goes to a company working in an academic partnership resulting in the development of real-time, near-patient blood propofol concentration monitoring devices Congratulations Somnus Scientific”.
Read MoreRT @GASPAnaesthesia: Congratulations @WhippsCrossHosp for Ditiching Desflurane. This will have a great impact in reducing the carbon footpr…
Read MoreBig news! At last nights MediLink Annual South West meeting Somnus Scientific won the 2022 award for "Partnership between Academia and Business". This means we are now a national finalist at the Birmingham event in June.
Read MoreDr Tim Craft is representing Somnus at the MediLink regional awards tonight. The keynote speaker is Hassan Chaudhury Digital Health Leader, Department for International Trade. This event is being held in partnership with the Health Tech Hub @UWEBristol with support from @sw_ahsn
Read MoreSomnus' CEO Dr Tim Craft is attending the annual MediLink SW meeting tonight where we have been shortlisted for the 2022 Medilink South West "Partnership between Academia and Business" Award.
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